How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

DNA has to be carefully organized and packaged so it will fit into the nucleus of cells; compacted DNA that's been organized with other proteins is known as chromatin. The structure of the genome can ...

Transcription and translation are two essential life processes for creating proteins, the cornerstone of any Genetics 101 class. Geneticists have been studying how the body makes copies of RNA and ...

Hypoxia-inducible factors (HIFs), ETS-1, MYC, and β-catenin act as master regulators that constitutively activate oncogenic ...

What happens on the atomic scale when DNA transcription is paused has been unveiled for the first time. (Nanowerk News) A detailed picture of what happens when DNA transcription is paused early in the ...

During transcription, DNA supercoiling occurs when torsional stress is introduced by the unzipping of a portion of the helix into two strands, one of which will be transcribed.

Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism ...

Transcription–replication collisions can occur owing to cis structural features, such as changes in DNA supercoiling, or secondary DNA structures, including hairpins, G-quadruplexes and RNA ...

DNA Methylation Market OverviewDNA methylation is a biological process in which methyl groups (CH3) are added to the DNA ...