Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general population and is ...

Zeng X. Unleashing the potential of exosome ncRNAs for early gastric cancer detection—a critical appraisal of machine learning approaches. Gut 2025;74:1191–1192.

Results We found that high intrahepatic uric acid contents were positively related to GSDMD-mediated pyroptosis in NASH mice (IDDF2024-ABS-0226 Figure 1. Intrahepatic uric acid is associated with ...

Objective IBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments.

The gut microbiota has been implicated in cancer and shown to modulate anticancer drug efficacy. Altered gut microbiota is associated with resistance to chemo drugs or immune checkpoint inhibitors ...

The Asia-Pacific region has the largest number of cases of colorectal cancer (CRC) and one of the highest levels of mortality due to this condition in the world. Since the publishing of two consensus ...

Background Double-balloon enteroscopy (DBE)-assisted endoscopic balloon dilatation (EBD) is a promising technique to manage small bowel stricture in patients with Crohn’s disease. This study will ...

Footnotes. Correction notice This article has been corrected since it published Online First. The seventh author's name has been corrected. Contributors PS, RB, TE and CH are responsible for the ...

Objective Therapeutic strategies silencing and reducing the hepatitis B virus (HBV) reservoir, the covalently closed circular DNA (cccDNA), have the potential to cure chronic HBV infection. We aimed ...

Liver fibrosis is characterised by the excessive deposition of extracellular matrix (ECM) in response to chronic and sustained liver damage, triggering a prolonged wound healing response. The ...

Background Ferric Carboxymaltose (Ferinject) is a commonly used intravenous iron preparation. Varying degrees of hypophosphataemia have been reported with Ferinject. This is thought to be due to FGF23 ...

Introduction Social distancing, staff shortages and patient isolation due to the Covid-19 pandemic has caused significant challenges in the National Health Service. The British Society of ...