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Gut1d
Extracellular vesicle-induced lipid dysregulation drives liver premetastatic niche formation in colorectal cancer
Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...
Gut6d
Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general population and is ...
gut.bmj3d
British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults | Gut
Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease worldwide. It can generally be diagnosed by blood testing and remedied by iron replacement therapy (IRT) using the ...
gut.bmj1d
COVID-19 and liver disease - Gut
Knowledge on SARS-CoV-2 infection and its resultant COVID-19 in liver diseases has rapidly increased during the pandemic. Hereby, we review COVID-19 liver manifestations and pathophysiological aspects ...
gut.bmj2d
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism | Gut
Objectives Gut microbiota is a key component in obesity and type 2 diabetes, yet mechanisms and metabolites central to this interaction remain unclear. We examined the human gut microbiome’s ...
gut.bmj6d
Biopsy and blood-based molecular biomarker of inflammation in IBD - Gut
Objective IBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments.
gut.bmj5d
The pathogenesis of duodenal gastric metaplasia: the role of local goblet cell transformation - Gut
BACKGROUND AND AIMS Gastric metaplasia is frequently seen in biopsies of the duodenal cap, particularly when inflamed or ulcerated. In its initial manifestation small patches of gastric foveolar cells ...
gut.bmj6d
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial - Gut
Background and aims Conventional hot snare endoscopic mucosal resection (H-EMR) is effective for the management of large (≥20 mm) non-pedunculated colon polyps (LNPCPs) however, electrocautery-related ...
gut.bmj3d
IDDF2024-ABS-0283 De novo discovery of C-Met—targeting peptides for 68Ga-PET imaging of hepatocellular carcinoma - Gut
Background Hepatocellular carcinoma (HCC) is the sixth most common cancer and the fourth leading cause of cancer-related death worldwide. Effective early diagnosis is hampered by the lack of ...
gut.bmj5d
IDDF2024-ABS-0226 High uric acid aggravates nonalcoholic steatohepatitis through trigging NLRP3-GSDMD-mediated pyroptosis | Gut
Results We found that high intrahepatic uric acid contents were positively related to GSDMD-mediated pyroptosis in NASH mice (IDDF2024-ABS-0226 Figure 1. Intrahepatic uric acid is associated with ...
gut.bmj6d
IDDF2022-ABS-0048 Clinical outcome of endoscopic balloon dilatation for small bowel stricture in Crohn’s disease using double-balloon enteroscopy | Gut
Background Double-balloon enteroscopy (DBE)-assisted endoscopic balloon dilatation (EBD) is a promising technique to manage small bowel stricture in patients with Crohn’s disease. This study will ...