Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Contributed by Gurudev S. Khush; received May 27, 2024; accepted July 26, 2024; reviewed by Paul Christou and Götz Hensel In line with intensified efforts to combat the multifaceted impacts of ...

Contributed by Chi-Ming Che; received October 6, 2023; accepted April 27, 2024; reviewed by Harry B. Gray and Yi Lu ...

Contributed by Ian J. Bateman; received April 20, 2024; accepted October 3, 2024; reviewed by Roy Brouwer, Catherine L. Kling, and Marije Schaafsma This contribution is part of the special series of ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

Meiotic recombination is an evolutionary-conserved process that shapes genetic variation in most eukaryotes. DNA is packaged into nucleosomes, and high levels of nucleosome occupancy suppress ...

This work was supported by the National Natural Science Foundation of China (32230008 to H.G.), the New Cornerstone Science Foundation (Grant No. NCI202235 to H.G.), and the Shenzhen Science and ...

The origin of evolutionary novelties is often underpinned by a complex set of changes. The genetic underpinnings comprise, for instance, gene or genome duplication, mutations, deletions, and ...

Sorting cells with target metabolic functions from a mutant pool exhibiting substantial genetic diversity is often the rate-limiting step in synthetic biology. Here, we developed a label-free, ...

Pigments and colors play a crucial role in nature, supporting functions such as camouflage, communication, mate attraction, and protection from radiation. Leucophores, which form uric acid crystals, ...

Room-temperature superconductors could revolutionize modern technology by enabling lossless power transmission, powerful magnets, advanced medical imaging (MRI), and quantum computing.

Developing oral biologics has long been a holy grail of protein engineering. Traditional antibodies are large and unstable in the presence of gastrointestinal proteases. Here, we present a strategy to ...