Fly one-way from Pittsburgh to St. Louis starting at $127. Bundle your Southwest Airlines® flight with a hotel or rental car booking and find even more savings.

There are 4 ways to get from Pittsburgh to St. Louis by plane, bus (Greyhound), train (Amtrak), or car. Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Cheap Flights from Pittsburgh (PIT) to St. Louis (STL) start at $66 for one-way and $120 for round trip. Earn your airline miles on top of our rewards!

Are you searching for American Airlines flights from Pittsburgh to Saint Louis? Find the best selections and fly in style.

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Pittsburgh to St. Louis. Discover the best prices and deals for you by selecting your travel dates. Only flying one-way? Below are some of the best one-way flight deals from Pittsburgh to St. Louis found on KAYAK recently.

Pittsburgh (PIT) to Saint Louis (STL) flight schedule. The monthly calendar shows every direct flight departure from Pittsburgh Airport (PIT) with all airlines. Click on a date to see a list of flights or search for the best prices.

Find United Airlines cheap flights from Pittsburgh to Saint Louis. Enjoy a Pittsburgh to Saint Louis modern flight experience in premium cabins with Wi-Fi.

Compare Pittsburgh to St Louis flight deals. Find the cheapest month or even day of the year to fly to St Louis. Book the best St Louis fare with no extra fees. Looking for a cheap last-minute deal or the best round-trip flight from Pittsburgh to St Louis? Find the lowest prices on one-way and round-trip tickets right here.

6 days ago · All direct (non-stop) flights from Pittsburgh to St. Louis. See airlines, aircrafts, flight time and distance, flight schedules and timetables.

Search and compare airfare from 1000+ airlines and travel sites to get the cheapest flights from Pittsburgh to St. Louis with momondo.